Neural Circuits and Cognition Lab
The goal of our research program is to understand how cognitive functions are mediated by interactions of cortical and subcortical circuits. Our primary focus is to elucidate how the brain pays attention to motivational salient stimuli and amplifies the associated cortical processing by engaging a key neural circuit we identified in recent years - salience-encoding neurons in the basal forebrain (BF). The laboratory combines multiple experimental approaches, including neuronal ensemble recording in behaving rats and mice, as well as behavioral, optogenetic, pharmacological and computational techniques. Our ultimate goal is to develop therapeutic interventions that can be used to alleviate impairments in attention control in conditions such as aging, schizophrenia and ADHD.
Updates & News
- 2019/03/25: Lab website updated!